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Therefore, the current study was designed to evaluate the nephroprotective activity of Dr. Balasubramanian Karthikeyan M Effect, Amaranthus hybridus, Diabetic Nephropathy, AYURVEDA have evidently revealed vasicine (peganine) to be derived from the anthranilic acid, while the remaining portion of the structure comprising of a pyrrolidine ring provided by ornithine. Pushal and mancha would probably be assigned to category II.Thirumalaiswamy Balasubramanian Department of Pharmacology Al Shifa College of Pharmacy Poonthavanam Post, Kizhattur Village Perinthalmanna, Malappuram Dist Kerala-679 325, India Tel: 919544496752 E-mail: [email protected] The probable mechanism of vasicine skeleton may be explained by virtue of the nucleophilic attack from the N-atom present in anthranilate upon the pyrrolidinium cation, ultimately followed by amide formation. Guatemala: Mo H department with information on site 19. On many saffron packaging labels, neither the ISO 3632 category nor the colouring strength (the measurement of crocin content) is displayed.For this reason, Pure Herbs are recommended for children ages 14 and above. Thus, in India, high-grade Kashmiri saffron is often sold and mixed with cheaper Iranian imports; these mixes are then marketed as pure Kashmiri saffron, a development that has cost Kashmiri growers much of their income.

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However, interestingly this pathway is not being adopted in ) is well known in Ayurveda for its beneficial effects in respiratory ailments, particularly as an expectorant in bronchitis. However, many growers, traders, and consumers reject such lab test numbers.

The leaves, flowers, fruits and roots are used extensively for treating cold, cough, whooping-cough, chronic bronchitis and asthma. Some people prefer a more holistic method of sampling batches of threads for taste, aroma, pliability, and other traits in a fashion similar to that practised by experienced wine tasters.

More and more interest is now growing about plant use as an alternative therapy for protecting kidney damage in patients with diabetes mellitus. Grading standards are set by the International Organization for Standardization, a federation of national standards bodies.

Reactive oxygen species (ROS) have been widely implicated in the pathogenicity of diabetes mellitus and its nephropathy. ISO 3632 deals exclusively with saffron and establishes three categories: III (poorest quality), II, and I (finest quality).

Vasaka grows throughout India, up to an altitude of 1,300 meters. However, ISO 3632 grade and colouring strength information allow consumers to make instant comparisons between the quality of different saffron brands, without needing to purchase and sample the saffron.

Vasaka contains the pyrroquinazoline alkaloids, including vasicine, vasicol and vasinone along with other minor constituents. In particular, consumers can work out value for money based on price per unit of colouring strength rather than price per gram, given the wide possible range of colouring strengths that different kinds of saffron can have.

Leaves possess antibacterial effect, cleansing effect and also help to reduce tissue swelling [5]. Saffron’s colouring strength can range from lower than 80 (for all category IV saffron) up to 200 or greater (for category I).

In Nigeria, leaves combined with condiments are used to prepare soup [6–8]. The world’s finest samples (the selected, most red-maroon, tips of stigmas picked from the finest flowers) receive colouring strengths in excess of 250, making such saffron over three times more powerful than category IV saffron.

All about Drugs, live, by DR ANTHONY MELVIN CRASTO, Worlddrugtracker, Helping millions, 9 million hits on google, pushing boundaries,2.5 lakh plus connections worldwide, 18 lakh plus VIEWS on this blog in 216 countries, The views expressed are my personal and in no-way suggest the views of the professional body or the company that I represent, USE CTRL AND KEY TO ENLARGE BLOG VIEW……………………A 90 % paralysed man in action for you, I am suffering from transverse mylitis and bound to a wheel chair, With death on the horizon, nothing will not stop me helping you, except God DR ANTHONY MELVIN CRASTO, Born in Mumbai in 1964 and graduated from Mumbai University, Completed his Ph. Countries producing less saffron do not have specialised words for different grades and may only produce one grade.

D from ICT, 1991, Matunga, Mumbai, India, in Organic Chemistry, The thesis topic was Synthesis of Novel Pyrethroid Analogues, Currently he is working with GLENMARK PHARMACEUTICALS LTD, Research Centre as Principal Scientist, Process Research (bulk actives) at Mahape, Navi Mumbai, India. Kulkarni, etc, He did custom synthesis for major multinationals in his career like BASF, Novartis, Sanofi, etc., He has worked in Discovery, Natural products, Bulk drugs, Generics, Intermediates, Fine chemicals, Neutraceuticals, GMP, Scaleups, etc, he is now helping millions, has 9 million plus hits on Google on all Organic chemistry websites. His New Drug Approvals, Green Chemistry International, All about drugs, Eurekamoments, Organic spectroscopy international, etc in organic chemistry are some most read blogs He has hands on experience in initiation and developing novel routes for drug molecules and implementation them on commercial scale over a 30 year tenure till date Dec 2017, Around 35 plus products in his career. Artisan producers in Europe and New Zealand have offset their higher labour charges for saffron harvesting by targeting quality, only offering extremely high grade saffron.

A number of clinical studies suggest that the antioxidants in medicinal plants are key factors in reducing the incidence of diabetic nephropathy. Venezuela (Bolivarian Republic of): EMRO ‐ Regional Office for the Eastern Mediterranean 1. Formerly there was also category IV, which was below category III.